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relapsing polychondritis

 

CLINICAL: painful erythema and edema involving both ears and nose, eventually leading to flabby ears and saddle nose

HISTOPATHOLOGY: mixed inflammatory infiltrate (lymphocytes, plasma cells, and neutrophils) involving the deep dermis and cartilage. Cartilage cell vacuolisation and pyknosis leading to total destruction and replacement by fibrous tissue

DIFFERENTIAL: chondrodermatitis nodularis chronica helicis


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