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NICH

noninvoluting congenital hemangioma

 

CLINICAL: NICH (noninvoluting congenital hemangioma) is a glut-1 negative congenital hemangioma that does not regress with time. RICH (rapidly involuting congenital hemangioma) and infantile hemangioma regress after birth.

HISTOPATHOLOGY: distinctive features include 1) prominent arteries and abnormal veins with arteriolobular and arteriovenous fistulae and 2) hobnail endothelial cells. However, NICH removed early (2-4 years) is often similar or histologically indistinguishable to RICH.

DIFFERENTIAL:
-  RICH (rapidly involuting congenital hemangioma)
-  infantile hemangioma

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