CLINICAL: NICH (noninvoluting congenital hemangioma) is a glut-1 negative congenital hemangioma that does not regress with time. RICH (rapidly involuting congenital hemangioma) and infantile hemangioma regress after birth.
HISTOPATHOLOGY: distinctive features include 1) prominent arteries and abnormal veins with arteriolobular and arteriovenous fistulae and 2) hobnail endothelial cells. However, NICH removed early (2-4 years) is often similar or histologically indistinguishable to RICH.
DIFFERENTIAL:
RICH (rapidly involuting congenital hemangioma)
infantile hemangioma
RETURN TO: vascular tumors