acute lymphoblastic leukemias
acute lymphoid leukemias
Types
B-cell acute lymphoblastic leukemia
T-cell acute lymphoblastic leukemia
Cytogenetics
11p13 (LMO2)
- t(7;11)(q35;p13) (/LMO2)
- t(11;14)(p13;q11) (LMO2/)
trisomies
- trisomy 4
deletions
- 9p21 deletion
- 9p21 maternal region preferentially deleted
Molecular biology
References
Pui CH, Relling MV, Downing JR. Acute lymphoblastic leukemia. N Engl J Med. 2004 Apr 8;350(15):1535-48. PMID: #15071128#
ALL: diffuse infiltration of bone marrow by lymphoblasts
Forum de l'article
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