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desoxyribonucleic acid

DNA

 

Definition: The molecule that encodes genetic information. DNA is a double-stranded molecule held together by weak bonds between base pairs of nucleotides.

The four nucleotides in DNA contain the bases: adenine (A), guanine (G), cytosine (C), and thymine (T). In nature, base pairs form only between A and T and between G and C; thus the base sequence of each single strand can be deduced from that of its partner.

See also

-  DNA repair
-  DNA methylation
-  DNA damage response pathways
-  DNA glycosylases
-  DNA double-strand break
-  DNA helicases
-  DNA damage
-  DNA loops
-  DNA repair nucleases
-  oxidative stress
-  DNA ligases
-  DNA mismatch repair
-  DNA double-strand break repair
-  DNA replication
-  DNA repair diseases
-  DNA methyltransferases
-  DNA hypermethylation
-  genome integrity

References

-  Szathmary E. Why are there four letters in the genetic alphabet? Nat Rev Genet. 2003 Dec;4(12):995-1001. PMID: #14631359#


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