Etiology:

 viral hepatitis

• cytomegalovirus hepatitis (CMV hepatitis)
• rubella virus hepatitis
• herpes simplex virus hepatitis (HSV hepatitis)
• HPV
• HHV-6 hepatitis
• varicella hepatitis
• coxsackievirus hepatitis
• echovirus hepatitis
• reovirus 3 hepatitis
• parvovirus B19 hepatitis
• HIV hepatitis
• enterovirus hepatitis
• paramyxovirus hepatitis
• hepatitis A
• hepatitis B
• hepatitis C (rare)

 bacterial hepatitis

• generalized bacterial sepsis
• syphilis (syphilitic hepatitis)
• listeriosis hepatitis
• tuberculosis (tuberculous hepatitis)

 parasitic hepatitis (protozoan hepatitis)

• toxoplasmosis hepatitis

 cholestasis

• biliary atresia
• choledochal cyst
• intrahepatic bile duct paucity and Alagille disease
• cystic fibrosis
• familial intrahepatic cholestatic syndromes (FIHC)
• bile acid synthetic diseases (inborn errors of bile acid synthesis)
• cystic fibrosis

 chromosomal anomalies

• trisomy 21
• trisomy 18
• monosomy X

 metabolic diseases

• alpha-1-antitrypsin deficiency
• galactosemia
• Niemann-Pick disease
• Gaucher disease
• mucolipidosis
• cerebrohepatorenal syndrome (Zellweger syndrome)
• acute tyrosinemia
• some mitochondriopathies
• some peroxysomopathies

 autoimmune diseases (immunohemolytic diseases)
 autoimmune hemolytic anemia (GCHAIHA)

• autoimmune hepatitis type II (LKM1+) (1)
• neonatal erythematosus lupus - systemic lupus (1,2,3)

 cardiovascuar diseases

• endocardial cushion defect
• anomalous pulmonary venous return

 neonatal hemochromatosis (fetal massive hepatic necrosis)

Associations

 neonatal hemochromatosis (idiopathic iron storage syndrome)
 Arnold-Chiari malformation

See also

 neonatl hepatitis