Definition: Ischemia is a loss of blood supply from impeded arterial flow or reduced venous drainage in a tissue. Ischemia compromises the supply not only of oxygen, but also of metabolic substrates, including glucose (normally provided by flowing blood).
Localization
cerebral ischemia
limbs ischemia
myocardic ischemia
visceral ischemia
See also
ischemic necrosis
References
Liang D, Dawson TM, Dawson VL. What have genetically engineered mice taught us about ischemic injury? Curr Mol Med. 2004 Mar;4(2):207-25. PMID: #15032714#
Salvemini D, Cuzzocrea S: Superoxide, superoxide dismutase and ischemic injury. Curr Opin Investig Drugs 3:886, 2002.
Sheridan AM, Bonventre JV: Cell biology and molecular mechanisms of injury in ischemic acute renal failure. Curr Opin Nephral Hypertens 9:427, 2000.