The nephrotic syndrome is characterized by massive proteinuria, which leads to hypoproteinemia/hypoalbunemia, hyperlipidemia with elevated cholesterols, triglycerides and other lipids, and edema.
Synopsis
minimal change glomerulopathy (+)
membranous glomerulopathy (+)
focal segmental glomerulosclerosis (+)
mesangioproliferative glomerulopathy (-)
Etiology
inherited nephrotic syndromes
paraneoplastic nephrotic syndrome (membranous glomerulonephritis 75%)
References
Salomon R, Gubler MC, Niaudet P. Genetics of the nephrotic syndrome. Curr Opin Pediatr. 2000 Apr;12(2):129-34. PMID: #10763762#