Definition: Small outpouchings of gallbladder mucosa that extend through the muscularis layer. It may be congenital.
Sinuses in the gallbladder. Normally occurring, microscopic pouches of the mucosa of the gallbladder. They may reach into and through the muscle wall. Prominence in the settings of inflammation and gallstone formation (e.g. chronic cholesystitis) suggest that they are acquired herniations.
References
Albores-Saavedra J, Shukla D, Carrick K, Henson DE. In Situ and Invasive Adenocarcinomas of the Gallbladder Extending Into or Arising From Rokitansky-Aschoff Sinuses: A Clinicopathologic Study of 49 Cases. Am J Surg Pathol. 2004 May;28(5):621-628. PMID: #15105650#