Classification

 adult-type renal clear cell carcinoma
 juvenile-type renal clear cell carcinoma (juvenile renal cell carcinoma)

• TFE3-associated renal cell tumor
• TFEB-associated renal cell tumor

Molecular biology

 3p25-26: VHL locus
 3p12-p21 locus (#10897333#)

Predisposition

 von Hippel-Lindau syndrome
 familial non-syndromic clear cell renal cell carcinoma (FNSCCRCC)

LOH

 3p LOH
 14q LOH
 18 LOH (19%)

• 18q21 LOH

See also

 Tumors

• renal tumors
• Carcinomas

References

 Bonne AC, Bodmer D, Schoenmakers EF, van Ravenswaaij CM, Hoogerbrugge N, van Kessel AG. Chromosome 3 translocations and familial renal cell cancer. Curr Mol Med. 2004 Dec;4(8):849-54. PMID: #15579032#

 Woodward ER. Familial non-syndromic clear cell renal cell carcinoma. Curr Mol Med. 2004 Dec;4(8):843-8. PMID: #15579031#