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loss of heterozygosity (LOH)

 

Features

-  LOH study
-  LOH regions
-  LOH database in human tumors

See also

-  allelotyping
-  laser capture microdissection and LOH
-  clustering of minimal deleted regions

References

-  Thiagalingam S, Foy RL, Cheng KH, Lee HJ, Thiagalingam A, Ponte JF. Loss of heterozygosity as a predictor to map tumor suppressor genes in cancer: molecular basis of its occurrence. Curr Opin Oncol. 2002 Jan;14(1):65-72. Review. Erratum in: Curr Opin Oncol 2002 May;14(3):374. PMID: #11790983#


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