Pathology

 TRC8 gene was interrupted by a t(3;8)(p14.2;q24.1) translocation in a family with hereditary renal and non-medullary thyroid cancer (#470981#, #12522559#).

 This translocation fuses FHIT with the patched-related gene TRC8 (#9689122#) with formation of the TRC8/FHIT fusion gene.

 TRC8/FHIT fusion gene in familial renal cell carcinoma (#470981#, #9689122#)

 TRC8/FHIT fusion gene in sporadic renal cell carcinoma (#9689122#)