MLL
The MLL gene is homologous to Drosophila trithorax and is likewise involved in embryo pattern formation.
| MLL/GMPS | ||
| MLL/FBP17 | ||
| MLL/LPP | ||
| MLL/GPH | ||
| MLL/PNUTL1 | ||
| MLL/CDK6 | ||
| MLL/LASP1 | ||
| MLL/GRAF | ||
| MLL/ABI1 | ||
| MLL/LAF4 | ins(11;2)(q23;q11.2q11.2) | acute lymphoblastic leukemia |
| MLL/CBL | - | acute myeloid leukemia |
| MLL/LARG | ||
| MLL/AF9 | t(9;11)(p22;q23) | acute myeloid leukemia |
| MLL/CALM | - | infant acute myeloid leukemia |
References
Collins EC, Rabbitts TH. The promiscuous MLL gene links chromosomal translocations to cellular differentiation and tumour tropism. Trends Mol Med. 2002 Sep;8(9):436-42. PMID: #12223315#
Make a note