Pathology
non-tumoral diseases
- infectious mononucleosis
- EBV chronic active infection
- oral hairy leukoplakia
- EBV-associated hemophagocytic syndrome (#12481907#, #12467966#, #11456362#, #8389318#)
- EBV hepatitis
EBV-associated tumors
- in immunocompromised host
- B cell malignancies
- EBV-associated smooth muscle cell tumors
- T cell malignancies
- extranodal NK/T cell lymphoma, nasal type
- EBV-associated hemophagocytic syndrome T cell lymphoma
- epithelial cell malignacies
-
EBV-associated undifferentiated carcinoma (EBV-associated undifferenciated carcinoma of nasopharyngeal type, UCNT)
- lymphoepithelioma-like carcinoma (salivary, thymus, lungs, stomach)
- EBV-associated mammary carcinoma (breast carcinoma)
- EBV-associated hepatocellualr carcinoma
References
Hammerschmidt W, Sugden B. Epstein-Barr virus sustains Burkitt's lymphomas and Hodgkin's disease. Trends Mol Med. 2004 Jul;10(7):331-6. PMID: #15242681#
Thorley-Lawson DA, Gross A. Persistence of the Epstein-Barr virus and the origins of associated lymphomas. N Engl J Med. 2004 Mar 25;350(13):1328-37. PMID: #15044644#
Khanna R, Tellam J, Duraiswamy J, Cooper L. Immunotherapeutic strategies for EBV-associated malignancies. Trends Mol Med. 2001 Jun;7(6):270-6. PMID: #11378517#
Gulley ML. Molecular diagnosis of Epstein-Barr virus-related diseases. J Mol Diagn. 2001 Feb;3(1):1-10. PMID: #11227065#
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