Definition: Hypoxia is a deficiency of oxygen, which causes cell injury by reducing aerobic oxidative respiration. Hypoxia is an extremely important and common cause of cell injury and cell death.

Features

 cellular hypoxia
 tissular hypoxia
 systemic hypoxia
 fetal hypoxia

See also

 Ischemia

References

 Pugh CW, Ratcliffe PJ. Regulation of angiogenesis by hypoxia: role of the HIF system. Nat Med. 2003 Jun;9(6):677-84. PMID: #12778166#

 Michiels C. Physiological and pathological responses to hypoxia. Am J Pathol. 2004 Jun;164(6):1875-82. PMID: #15161623#

 Poellinger L, Johnson RS. HIF-1 and hypoxic response: the plot thickens. Curr Opin Genet Dev. 2004 Feb;14(1):81-5. PMID: #15108809#

 Li C, Jackson RM: Reactive species mechanisms of cellular hypoxia-reoxygenation injury. Am J Physiol Cell Physiol 282:C227, 2002.