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intraductal carcinoma of the oral cavity

 
Pure in situ form of salivary duct carcinoma.

Synopsis

-  crowded and smooth-contoured epithelial units exhibiting a fenestrated or cribriform pattern
-  +/- comedonecrosis
-  layer of myoepithelial cells demonstrated by immunostaining for p63 and actin, indicating absence of an invasive component.

Prognosis

-  good prognosis after local excision

References

-  Cheuk W, Miliauskas JR, Chan JK. Intraductal carcinoma of the oral cavity: a case report and a reappraisal of the concept of pure ductal carcinoma in situ in salivary duct carcinoma. Am J Surg Pathol. 2004 Feb;28(2):266-70. PMID: #15043319#


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