Etiology:

 infectious systemic granulomatoses

• tuberculosis

 systemic tuberculoid granulomatoses

• chronic familial granulomatosis
• sarcoidosis
• necrotizing sarcoid granulomatosis
• Crohn disease
• familial juvenile systemic granulomatosis (FJGS) (Blau syndrome) (CARD15 mutations)

 systemic necrotizing granulomatosis
 Wegener granulomatosis
 Churg-Strauss angiitis

 tumoral systemic granulomatoses

• lymphomatoid granulomatosis
• T-cell lymphomas

 miscellaneous

• lipogranulomatoses
• hyalinizing plasmacytic granulomatosis (#2451439#)
• familial juvenile systemic granulomatosis (FJSG)

 systemic histiocytoses

• langerhans histiocytosis
• non-Langerhans cell histiocytoses
  • Erdheim-Chester disease
  • systemic juvenile xanthogranuloma
  • necrobiotic xanthogranuloma
  • adult disseminated xanthoma