congenital fibrosarcoma
infantile fibrosarcoma
Localization
soft tissues
digestive congenital fibrosarcoma
- duodenal congenital fibrosarcoma (#1185470#)
- jejunal congenital fibrosarcoma (#12776248#)
Cytogenetics
translocation t(12;15)(p13;q25) with ETV6/NTRK3 fusion gene
trisomy 11, trisomy 8, trisomy 17 and trisomy 20
Molecular biology
ETV6/NTRK3 fusion gene by translocation t(12;15)(p13;q25)
References
Bourgeois JM, Knezevich SR, Mathers JA, Sorensen PH. Molecular detection of the ETV6-NTRK3 gene fusion differentiates congenital fibrosarcoma from other childhood spindle cell tumors. Am J Surg Pathol. 2000 Jul;24(7):937-46. PMID: #10895816#
Herringbone pattern in a congenital fibrosarcoma.
Herringbone pattern in a congenital fibrosarcoma.
ETV6-NTRK3+ congenital fibrosarcoma
ETV6-NTRK3+ congenital fibrosarcoma
ETV6-NTRK3+ congenital fibrosarcoma
ETV6-NTRK3+ congenital fibrosarcoma
Negative desmin in an ETV6-NTRK3+ congenital fibrosarcoma
HHF35 actins+ in an ETV6-NTRK3+ congenital fibrosarcoma
Smooth muscle actin+ in an ETV6-NTRK3+ congenital fibrosarcoma
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