cutaneous GVHD
Acute phase
eosinophilic necrotic keratinocytes
satellite cell necrosis
lymphocyte exocytosis in epidermis
sparse, diffuse lymphocytic infiltrate in the upper dermis
vacuolar degeneration of basac cells
Chronic phase
acanthosis
Civatte bodies
cell necrosis in the basal layer
subepidermal mononuclear cell infiltrate
areas of separation of the basal layer from the dermal papillae
Late sclerotic stage
epidermal atrophy
thickened dermis
hyalinized collagen bundles extending into the subcutaneous tissue
Cutaneous GVH
Cutaneous GVH
Cutaneous GVH
Cutaneous GVH
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