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pulmonary arterial occlusive disease

pulmonary arterial occlusive vascular disease

 
Post-chemotherapy disorder

Etiology

-  chemotherapy

Synopsis

Small pulmonary arteries

-  diffuse medial hypertrophy
-  diffuse peripheral muscularization
-  very extensive concentric intimal fibrosis
-  focal eccentric fibrosis evolving from organizing thrombi
-  pulmonary veins normal

References

-  Bentur L, Cullinane C, Wilson P, Greenberg M, O'Brodovich H, Silver MM. Fatal pulmonary arterial occlusive vascular disease following chemotherapy in a 9-month-old infant. Hum Pathol. 1991 Dec;22(12):1295-8. PMID: #1748437#



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