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infantile hemangioma

 

CLINICAL: The typical infantile hemangioma appears postnataly, grows quickly, and regresses gradually in the first few years of life. Approximately one third of IH are present at birth. There are other vascular tumors; RICH (rapidly involuting congenital hemangioma) and NICH (noninvoluting congenital hemangioma) that are fully grown at birth and behave differently from the common infantile hemangioma.

HISTOPATHOLOGY: these tumors are highly cellular, involving the dermis, often with extension into the subcutis. The tumor has a lobular architecture and plump endothelial cells. The latter cells express glut-1 antigens throughout the life of this tumor.

DIFFERENTIAL:
-  NICH
-  RICH

RETURN TO: vascular tumors

References

-  Dadras SS, North PE, Bertoncini J, Mihm MC, Detmar M. Infantile hemangiomas are arrested in an early developmental vascular differentiation state. Mod Pathol. 2004 Sep;17(9):1068-79. PMID: #15143338#


Infantile hemangioma

Infantile hemangioma

Infantile hemangioma

GLUT1 positivity in nfantile hemangioma

Infantile hemangioma
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