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hepatic fibrosis

liver fibrosis, liver fibrogenesis

 

Topography

-  portal fibrosis
-  periportal fibrosis
-  septal hepatic fibrosis
-  portal and septal fibrosis (perilobular fibrosis)
-  sinuosidal fibrosis (perisinusoidal fibrosis)
-  pericentral fibrosis
-  hepatic phlebosclerosis

Predisposition

-  C5 (Complement factor 5) gene variants

References

-  Hillebrandt S, Wasmuth HE, Weiskirchen R, Hellerbrand C, Keppeler H, Werth A, Schirin-Sokhan R, Wilkens G, Geier A, Lorenzen J, Kohl J, Gressner AM, Matern S, Lammert F. Complement factor 5 is a quantitative trait gene that modifies liver fibrogenesis in mice and humans. Nat Genet. 2005 Aug;37(8):835-43. PMID: #15995705#


Hepatic fibrosis

Hepatic fibrosis in Ellis-van Creveld syndrome - Cholestatic cirrhosis

Portal fibrosis in ARPKD at 21 weeks - Congenital hepatic fibrosis is associated with ductal plate malformation

Fetal hepatic fibrosis at 29 weeks

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