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EWS/FLI1

EWS/FLI-1

 

Pathology

-  EWS/FLI1 fusion gene in Ewing sarcoma/peripheral primitive neuroectodermal tumors
-  EWS/FLI1 fusion gene in one case of solid pseudopapillary tumor of the pancreas (#11000339#)

Biology

-  Ewing tumor fusion proteins block the differentiation of pluripotent marrow stromal cells (#12839926#)
-  EWS/FLI-1 fusion gene switches the differentiation program of neuroblastomas to Ewing sarcoma/peripheral primitive neuroectodermal tumors (#14973077#)

References

-  Rorie CJ, Thomas VD, Chen P, Pierce HH, O'Bryan JP, Weissman BE. The Ews/Fli-1 fusion gene switches the differentiation program of neuroblastomas to Ewing sarcoma/peripheral primitive neuroectodermal tumors. Cancer Res. 2004 Feb 15;64(4):1266-77. PMID: #14973077#



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