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chronic pneumonitis of infancy

 

Microscop

-  interstitial thickening
-  alveolar infiltrate
-  alveolar proteinaceous material
-  hyeprplasia of type II pneumocytes

Molecular biology

-  mutation in the surfactant protein C gene SP-C associated with familial interstitial lung disease

References

-  Nogee LM, Dunbar AE 3rd, Wert SE, Askin F, Hamvas A, Whitsett JA. A mutation in the surfactant protein C gene associated with familial interstitial lung disease. N Engl J Med. 2001 Feb 22 ;344(8):573-9. PMID : #11207353#


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