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intramuscular myxoma

 
Intramuscular myxoma is a benign soft-tissue tumor that presents as a deeply seated mass confined to skeletal muscle.

Synopsisi

-  hypocellular, hypovascular regions
-  cytologically bland stellate and bipolar fibroblasts separated by abundant extracellular myxoid matrix
-  areas of increased cellularity and vascularity that can lead to a mistaken diagnosis of sarcoma

Differential diagnosis

-  myxofibrosarcoma
-  low-grade fibromyxoid sarcoma
-  myxoid liposarcoma

Prognosis

Surgical excision is virtually always curative. Recurrence, even after incomplete resection, is exceptional.

References

-  Nielsen GP, O'Connell JX, Rosenberg AE. Intramuscular myxoma: a clinicopathologic study of 51 cases with emphasis on hypercellular and hypervascular variants. Am J Surg Pathol. 1998 Oct;22(10):1222-7. PMID: #9777984#


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