Fascins are actin-bundling proteins. Fascin-1 is expressed by dendritic cells in the blood and in tissues.
Members
| FSCN1 | FSCN2 |
Expression in tumors
juvenile xanthogranulomas (JXG) (#10463281#)
Rosai-Dorfman lesions (#10463281#)
soft tissue dendrocytomas (#10463281#)
Erdheim-Chester disease
References
Jaffe R, DeVaughn D, Langhoff E. Fascin and the differential diagnosis of childhood histiocytic lesions. Pediatr Dev Pathol. 1998 May-Jun;1(3):216-21. PMID: #10463281#