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fascins

 

Fascins are actin-bundling proteins. Fascin-1 is expressed by dendritic cells in the blood and in tissues.

Members

FSCN1 FSCN2

Expression in tumors

-  juvenile xanthogranulomas (JXG) (#10463281#)
-  Rosai-Dorfman lesions (#10463281#)
-  soft tissue dendrocytomas (#10463281#)
-  Erdheim-Chester disease

References

-  Jaffe R, DeVaughn D, Langhoff E. Fascin and the differential diagnosis of childhood histiocytic lesions. Pediatr Dev Pathol. 1998 May-Jun;1(3):216-21. PMID: #10463281#


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