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malignant myopericytoma

 

Epidemiology

-  no sex predominance (#12405913#)
-  median age 67 years (range 19-81 years) (#12405913#)
-  neck, arm, thigh and foot(#12405913#)

Synopsis

-  highly mitotic myoid-appearing ovoid-to-spindle cells showing at least focally striking perivascular orientation resembling that seen in benign myopericytoma
-  fascicular +/-
-  thin-walled branching vessels +/-

Immunochemistry

-  positivity for smooth muscle actin
-  +/- dot-like desmin positivity

Prognosis

-  possible metastases (#12405913#)

References

-  McMenamin ME, Fletcher CD. Malignant myopericytoma: expanding the spectrum of tumours with myopericytic differentiation. Histopathology. 2002 Nov;41(5):450-60. PMID: #12405913#



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