Classification

 prostatic adenocarcinomas

• classical prostatic adenocarcinomas
• prostatic adenoid cystic carcinoma / prostatic basal cell carcinoma

 prostate carcinoma with squamous differentiation (#15105655#)

Molecular biology

 DNA microarrays: #12084220#
 Proteomics: #11721637#

Susceptibility

 MSR1 gene coding for macrophage scavenger receptor 1 (#12471593#)
 RNASEL (HPC1) gene variants (#12145743#)
 BRCA2 mutations (2%)

Aggressiveness

 ch. 7
 19q

References

 Schaid DJ. The complex genetic epidemiology of prostate cancer. Hum Mol Genet. 2004 Apr 1;13 Spec No 1:R103-21. Epub 2004 Jan 28. PMID: #14749351#

 Gonzalgo ML, Isaacs WB. Molecular pathways to prostate cancer. J Urol. 2003 Dec;170(6 Pt 1):2444-52. PMID: #14634448#

 Nelson WG, De Marzo AM, Isaacs WB. N Engl J Med. 2003 Jul 24;349(4):366-81. PMID: #12878745#

 Nwosu V, Carpten J, Trent JM, Sheridan R. Heterogeneity of genetic alterations in prostate cancer: evidence of the complex nature of the disease. Hum Mol Genet. 2001 Oct 1;10(20):2313-8. PMID: #11673416#

 Rubin MA. Use of laser capture microdissection, cDNA microarrays, and tissue microarrays in advancing our understanding of prostate cancer. J Pathol. 2001 Sep;195(1):80-6. PMID: #11568894#