Definition: A type of junction between two cells through which ions and small molecules can pass.

Gap-junction intercellular communication allows a mechanism of synchronized cellular response to a variety of intercellualr signals by regulating the direct passage of low-molecular-weight metabolites (< 1000 daltons) and ions between the cytoplasm of adjacent cells.

See also

 connexins

References

 Sohl G, Maxeiner S, Willecke K. Expression and functions of neuronal gap junctions. Nat Rev Neurosci. 2005 Mar;6(3):191-200. PMID: #15738956#

 van Steensel MA. Gap junction diseases of the skin. Am J Med Genet. 2004 Nov 15;131C(1):12-9. PMID: #15468169#

 Falk M. Genetic tags for labelling live cells : gap junctions and beyond. Trends Cell Biol. 2002 Sep ;12(9):399-404. PMID : #12220850#