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VCL

MIM.193065

vinculin 10q22.1-q23

 

Vinculin is a cytoskeletal protein associated with the cytoplasmic face of both cell-cell and cell-extracellular matrix adherens-type junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane.

See also

-  TLNs: TLN1, TLN2
-  ITGs
-  VILs: VIL1, VIL2

References

-  Bailly M. Connecting cell adhesion to the actin polymerization machinery: vinculin as the missing link? Trends Cell Biol. 2003 Apr;13(4):163-5. PMID: #12667752#


Vinculin in focal contacts - (From Rockfeller University)

Vinculin in adherens junctions

Vinculin (VCL) and the dystrophin-glycoprotein complex

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