Clathrin-coated vesicles (CCVs) play important roles in nutrient uptake, downregulation of signaling receptors, pathogen invasion and biogenesis of endosomes and lysosomes.

Features

 endocytic CCV formation have emerged
 CCV formation at the Golgi
 endosomes and endocytic CCV formation
 ENTH/ANTH proteins
 clathrin adaptator proteins

References

 Robinson MS. Adaptable adaptors for coated vesicles. Trends Cell Biol. 2004 Apr;14(4):167-74. PMID: #15066634#

 Duncan MC, Payne GS. ENTH/ANTH domains expand to the Golgi. Trends Cell Biol. 2003 May;13(5):211-5. PMID: #12742163#

 Smythe E. Regulating the clathrin-coated vesicle cycle by AP2 subunit phosphorylation. Trends Cell Biol. 2002 Aug;12(8):352-4. PMID: #12191904#