ACVRLK1
ALK1, ACVRL1, ALK-1, activin receptor-like kinase 1, type II-like activin A receptor kinase 1
Activin A receptor, type II-like kinase 1 (also called activin receptor-like kinase 1) is a type I cell-surface receptor for the TGF-beta superfamily of ligands.
Activin A receptor type II-like kinase 1 (ALK-1) or activin receptor-like kinase 1 (ACVRLK1) is a type I cell-surface receptor for the TGF-beta superfamily of ligands (MIM.190180).
It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail.
The ALK1 ligand in vivo is unknown (2003).
mutations in hereditary hemorrhagic telangiectasia type 2 (HHT2) (MIM.600376)
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