Forkhead-box (FOX) superfamily genes are implicated in carcinogenesis through gene amplification, retroviral integration and chromosomal translocation. FOX superfamily genes within the human genome are classified into 17 or 18 families, designated FOX# (# is alphabet A-Q or R).

Members

Pathology

 FOX01A (FKHR) (MIM.136533)

• gene fusion PAX3/FOX01A in alveolar rhabdomyosarcoma by t(12;13)

References

 Lehmann OJ, Sowden JC, Carlsson P, Jordan T, Bhattacharya SS. Fox's in development and disease. Trends Genet. 2003 Jun;19(6):339-44. PMID: #12801727#