Autosomal dominant tumor predisposition syndrome.
Synopsis
congenital hypertrophy of retinal pigment epithelium (CHRPE)
supernumerary teeth
unerupted teeth
dental caries
odontomas
mammary fibrosis
multiple colonic adenomatous polyps
multiple gastric polyps
multiple duodenal polyps
mesenteric fibromatosis
skull osteomas, especially involving the mandibular angle
endosteal and exosteal osteomas
epidermoid inclusion cysts
fibromas
lipomas
lipofibromas
increased skin pigmentation
keloids
tumors
References
Fodde R, Smits R. Disease model: familial adenomatous polyposis. Trends Mol Med. 2001 Aug;7(8):369-73. PMID: #11516998#
Fearnhead NS, Britton MP, Bodmer WF. The ABC of APC. Hum Mol Genet. 2001 Apr;10(7):721-33. PMID: #11257105#