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NF-kappaB

NFKB complex

 

Subunits

NFKBs NFKBA NFKBB

References

-  von Bernuth H, Puel A, Ku CL, Yang K, Bustamante J, Chang HH, Picard C, Casanova JL. Septicemia without sepsis: inherited disorders of nuclear factor-kappa B-mediated inflammation. Clin Infect Dis. 2005 Nov 15;41 Suppl 7:S436-9. PMID: #16237643#

-  Perkins ND. NF-kappaB: tumor promoter or suppressor? Trends Cell Biol. 2004 Feb;14(2):64-9. PMID: #15102437#

-  Kutuk O, Basaga H. Inflammation meets oxidation: NF-kappaB as a mediator of initial lesion development in atherosclerosis. Trends Mol Med. 2003 Dec;9(12):549-57. PMID: #14659470#

-  Tian B, Brasier AR. Identification of a nuclear factor kappa B-dependent gene network. Recent Prog Horm Res. 2003;58:95-130. PMID: #12795416#

-  Young MR, Yang HS, Colburn NH. Promising molecular targets for cancer prevention: AP-1, NF-kappa B and Pdcd4. Trends Mol Med. 2003 Jan;9(1):36-41. PMID: #12524209#

-  Smahi A, Courtois G, Rabia SH, Doffinger R, Bodemer C, Munnich A, Casanova JL, Israel A. The NF-kappaB signalling pathway in human diseases: from incontinentia pigmenti to ectodermal dysplasias and immune-deficiency syndromes. Hum Mol Genet. 2002 Oct 1;11(20):2371-5. PMID: #12351572#

-  Orlowski RZ, Baldwin AS Jr. NF-kappaB as a therapeutic target in cancer. Trends Mol Med. 2002 Aug;8(8):385-9. PMID: #12127724#

-  Jobin C, Sartor RB. The I kappa B/NF-kappa B system: a key determinant of mucosalinflammation and protection. Am J Physiol Cell Physiol. 2000 Mar;278(3):C451-62. PMID: #10712233#

-  Israel A. The IKK complex: an integrator of all signals that activate NF-kappaB ? Trends Cell Biol. 2000 Apr;10(4):129-33. PMID: #10740266#

-  Foo SY, Nolan GP. NF-kappaB to the rescue: RELs, apoptosis and cellular transformation. Trends Genet. 1999 Jun;15(6):229-35. PMID: #10354583#


NFkappaB signaling pathway - From Biocarta

NF-kappaB activation by RIPK2 and CARD15

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