Synopsis

 perinuclear pattern with anti-neutrophil cytoplasmic antibody (p-ANCA +) (pANCA-associated microscopic polyangiitis)
 disseminated intravascular coagulation (DIC)with marked systemic bleeding (#14518675#)

 massive myocardial necrosis

 pulmonary lesions

• pulmonary capillaritis
• necrotizing alveolar capillaritis
• diffuse alveolar hemorrhage (DAH)
• pulmonary interstitial fibrosis (#12527637#)

 peripheral neuropathy
 crescentic glomerulonephritis
 glomerulonephritis associated with small vessel vasculitis
 limited cutaneous systemic sclerosis

Associations

 cryptogenic fibrosing alveolitis
 late emergence of generalised Wegener's granulomatosis

References

 Jennette JC, Thomas DB, Falk RJ. Microscopic polyangiitis (microscopic polyarteritis). Semin Diagn Pathol. 2001 Feb;18(1):3-13. PMID: #11296991#