Cellular cholesterol homeostasis is maintained through activation of the designated sterol regulatory element binding proteins and liver X receptor transcriptional pathways.

Features

 cholesterol metabolism
 cholesterol biosynthesis
 high-density lipoprotein cholesterol
 biliary acids metabolism

Pathology

 cholesterol metabolism and Alzheimer disease
 cholesterol metabolism and prostatic carcinoma
 cholesterol metabolism and atherosclerosis

See also

 cholesterol storage diseases
 cholesterol accumulation
 cholesterol crystals

References

 Anderson RG. Joe Goldstein and Mike Brown: from cholesterol homeostasis to new paradigms in membrane biology. Trends Cell Biol. 2003 Oct;13(10):534-9. PMID: #14507481#

 Kaul D. Cholesterol-receptor-mediated genomics in health and disease. Trends Mol Med. 2003 Oct;9(10):442-9. PMID: #14557057#

 Poirier J. Apolipoprotein E and cholesterol metabolism in the pathogenesis and treatment of Alzheimer's disease. Trends Mol Med. 2003 Mar;9(3):94-101. PMID: #12657430#

 Oram JF. Molecular basis of cholesterol homeostasis: lessons from Tangier disease and ABCA1. Trends Mol Med. 2002 Apr;8(4):168-73. PMID: #11927274#