Immunochemistry

A103 is a melanocyte-associated monoclonal antibody that recognizes the Melan-A/MART-1 antigen in melanomas.

Expression in tumors

 melanoma
 sex cord stromal tumors of the ovary (SCSTs) (#12966351#)
 adrenal cortical tumors (#12808065#)

• adrenal cortical carcinoma

References

 Yan S, Brennick JB. False-positive Rate of the Immunoperoxidase Stains for MART1/MelanA in Lymph Nodes. Am J Surg Pathol. 2004 May;28(5):596-600. PMID: #15105646#

 Busam KJ, Iversen K, Coplan KA, Old LJ, Stockert E, Chen YT, McGregor D, Jungbluth A. Immunoreactivity for A103, an antibody to melan-A (Mart-1), in adrenocortical and other steroid tumors. Am J Surg Pathol. 1998 Jan;22(1):57-63. PMID: #9422316#