Immunochemistry

 deregulated expression of cell cycle-associated proteins (#11235905#)

Cytogenetics

 t(11;22)(q24;q12) translocation (#11000339#)

Molecular biology

 EWS/FLI-1 fusion transcript (#11000339#)
 beta-catenin gene (CTNNB1) mutation (83%) (#11943721#, #11731417#)

Differential diagnosis

 adrenal pheochromocytoma (#15182415#)

References

 Tang LH, Aydin H, Brennan MF, Klimstra DS. Clinically aggressive solid pseudopapillary tumors of the pancreas: a report of two cases with components of undifferentiated carcinoma and a comparative clinicopathologic analysis of 34 conventional cases. Am J Surg Pathol. 2005 Apr;29(4):512-9. PMID: #15767807#

 Klimstra DS, Wenig BM, Heffess CS. Solid-pseudopapillary tumor of the pancreas: a typically cystic carcinoma of low malignant potential. Semin Diagn Pathol. 2000 Feb;17(1):66-80. PMID: #10721808#

 Lieber MR, Lack EE, Roberts JR Jr, Merino MJ, Patterson K, Restrepo C, Solomon D, Chandra R, Triche TJ. Solid and papillary epithelial neoplasm of the pancreas. An ultrastructural and immunocytochemical study of six cases. Am J Surg Pathol. 1987 Feb;11(2):85-93. PMID: #3812876#