The signal transducer and activator of transcription (STATs) proteins are latent cytoplasmic signal-dependent transcription-factor pathways. In addition to several roles in normal cell decisions, dysregulation of STAT function contributes to human disease.
See also
JAKs
JAKs/STATs signaling pathways
References
Yu H, Jove R. The STATs of cancer--new molecular targets come of age. Nat Rev Cancer. 2004 Feb;4(2):97-105. PMID: #14964307#
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