Etiology
duplication or deletion of the proteolipid protein gene PLP1
References
Yool DA, Edgar JM, Montague P, Malcolm S. The proteolipid protein gene and myelin disorders in man and animal models. Hum Mol Genet. 2000 Apr 12;9(6):987-92. PMID: #10767322#
Woodward K, Malcolm S. Proteolipid protein gene: Pelizaeus-Merzbacher disease in humans and neurodegeneration in mice. Trends Genet. 1999 Apr;15(4):125-8. PMID: #10203813#