Locaization

 hepatic macrophages

• hepatic ceroid-laden macrophages
• portal lipid-laden macrophages

 renal macrophages

• foamy macrophages in renal tubules

Variants

 siderophages
 lipid-laden marcophages (foamy macrophages)
 ceroid-laden macrophages
 epithelioid cells
 enlarged macrophages
 cellular debris-laden macrophages

Immunophenotype

 CD68+
 HAM-56+
 alpha 1-antitrypsin +
 alpha 1-antichymotrypsin +
 lisozyme +
 alpha-subunit of S-100 protein +
 CD1a-

Pathology

 macrophagic activation syndrome
 histiocytic tumors

Localization

 hepatic macrophages
 pulmonary macrophages
 splenic macrophages

See also

 Histiocytes

• dendritic cells

 tumor-educated macrophages

References

 Vignery A. Macrophage fusion: are somatic and cancer cells possible partners? Trends Cell Biol. 2005 Apr;15(4):188-93. PMID: #15817374#

 Fujiwara N, Kobayashi K. Macrophages in inflammation. Curr Drug Targets Inflamm Allergy. 2005 Jun;4(3):281-6. PMID: #16101534#