Risk foactors

 hypertension
 hypercholesterolemia

Susceptibility loci

 apolipoprotein E type 4 locus (familail and sporadic AD)
 HMGR gene locus (sporadic AD)

early-onset AD

 2q34 (#14564669#)

late-onset familial AD (LOFAD)

 apolipoprotein E type 4 locus
 19p13.2 (#15248153#)

very-late-onset AD

 15q22 (#14564669#)

References

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