Localization
Susceptibility
locus 1q23: polymorphism at the C-reactive protein locus (#14645206#)
locus 1q31
locuss 1q41-q42
locus 2q34-q35: SLEN2
locus 2q37.3
locus 4p16-p15.2
locus 10q22.3: SLEN1
locus 11p15.5: SLEN3
locus 11q14
locus 12q24
Polymorphisms in the tyrosine kinase 2 gene (TYK2) (#15657875#)
Polymorphisms in interferon regulatory factor 5 gene (IRF5) (#15657875#)
References
Prokunina L, Alarcon-Riquelme M. The genetic basis of systemic lupus erythematosus--knowledge of today and thoughts for tomorrow. Hum Mol Genet. 2004 Apr 1;13 Spec No 1:R143-8. PMID: #14764622#