Etiology

 mutations of CRYM (#12471561#)
 mutations of TMIE (transmembrane inner ear expressed gene) (#12145746#)
 connexinopathies
 autosomal dominant nonsyndromic sensorineural deafness (MIM.601316)

• EYA4 mutations

References

 Ben-Yosef T, Friedman TB. The genetic bases for syndromic and nonsyndromic deafness among Jews. Trends Mol Med. 2003 Nov;9(11):496-502. PMID: #14604828#

 Ahituv N, Avraham KB. Mouse models for human deafness: current tools for new fashions. Trends Mol Med. 2002 Sep;8(9):447-51. PMID: #12223317#

 Morton CC. Genetics, genomics and gene discovery in the auditory system. Hum Mol Genet. 2002 May 15;11(10):1229-40. PMID: #12015283#

 Rabionet R, Lopez-Bigas N, Arbones ML, Estivill X. Connexin mutations in hearing loss, dermatological and neurological disorders. Trends Mol Med. 2002 May;8(5):205-12. PMID: #12067629#

 Steel KP, Bussoli TJ. Deafness genes: expressions of surprise. Trends Genet. 1999 Jun;15(6):207-11. PMID: #10354578#

 Kalatzis V, Petit C. The fundamental and medical impacts of recent progress in research on hereditary hearing loss. Hum Mol Genet. 1998;7(10):1589-97. PMID: #9735380#