Target genes
TCF3 (E2A)
LYL1
Pathology
19p13 rearrangements in leukemias
- t(1;19)(q23 ;p13) in acute pre-B lymphoblastic leukemia leukemia (B-ALL) (TCF3/PBX1 fusion gene)
- t(7;19)(q34 ;p13) in T-cell acute lymphoblastic leukemia (T-ALL) (LYL1/TCRB fusion gene)