Human pathology

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12q13-22 amplification

12q13-22 amplicon

The 12q13-22 amplicons are discontinuous and there are non-amplified marker loci between the amplified marker loci.

Tumors

- liposarcomas

References

- Wolf M, Aaltonen LA, Szymanska J, Tarkkanen M, Blomqvist C, Berner JM, Myklebost O, Knuutila S. Complexity of 12q13-22 amplicon in liposarcoma: microsatellite repeat analysis. Genes Chromosomes Cancer. 1997 Jan;18(1):66-70. PMID: 8993982