Pathology
11q13 rearrangements
-
t(11;14)(q13;q32) in B-cell proliferations
- B-cell lymphomas
- multiple myeloma
NUMA1 rearrangements at 11q13
- NUMA1/RARA fusion gene by t(11;17)(q13;q21) in acute promyelocytic leukemia (APL) (NUMA1 at 11q13 and RARA at 17q21).
11q13 amplicon
11q13 LOH
- parathyroid adenoma
- tumors in multiple endocrine neoplasia type 1 (MEN1)
Target genes