tumoral 13q deletion
Bands 13q12-22 are frequently affected.
benign lipomatous tumors and low-malignant lipomatous tumors
- ordinary lipomas
- spindle cell/pleomorphic lipomas
- myxolipomas
- angiomyxolipoma
- atypical lipomatous tumor
NB: Deletions and structural rearrangements of the long arm of chromosome 13 are frequently observed in benign and low-malignant lipomatous tumors, but nothing is known about their molecular genetic consequences.
Target genes
RB1
BRCA2 in 13q12
lipoma HMGIC fusion partner (LHFP) in 13q13