tRNA
transfert RNA
Definition: tRNA are a class of RNA having structures with triplet nucleotide sequences that are complementary sequences to the triplet nucleotide coding sequences of mRNA.
The role of tRNAs in protein synthesis is to bond with amino acids and transfer them to the ribosomes, where proteins are assembled according to the genetic code carried by mRNA.
Pathology of tRNA metabolism
pathology of aminoacyl-tRNA synthetases
- - glycyl tRNA synthetase mutations in Charcot-Marie-Tooth disease type 2D (CMT2D) and distal spinal muscular atrophy type V (DSMA5) (12690580)