t(7;16)(q34;p11)
low-grade fibromyxoid sarcoma (LGFMS)
- LGFMS is a rare metastasizing soft tissue tumor with deceptively bland histologic features.
hyalinizing spindle cell tumor with giant rosettes (HSCT)
- HSCT is thought to be a LGFMS closely related tumor differing only by the presence of collagen rosettes.
References
Guillou L, Benhattar J, Gengler C, Gallagher G, Ranchere-Vince D, Collin F, Terrier P, Terrier-Lacombe MJ, Leroux A, Marques B, Aubain Somerhausen Nde S, Keslair F, Pedeutour F, Coindre JM. Translocation-positive low-grade fibromyxoid sarcoma: clinicopathologic and molecular analysis of a series expanding the morphologic spectrum and suggesting potential relationship to sclerosing epithelioid fibrosarcoma: a study from the French Sarcoma Group. Am J Surg Pathol. 2007 Sep;31(9):1387-402. PMID: 17721195
Reid R, de Silva MV, Paterson L, Ryan E, Fisher C. Low-grade fibromyxoid sarcoma and hyalinizing spindle cell tumor with giant rosettes share a common t(7;16)(q34;p11) translocation. Am J Surg Pathol. 2003 Sep;27(9):1229-36. PMID: 12960807